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Zach Cregger's 'Resident Evil' nets $26.3 million on its opening day, dominating the box office and setting franchise records.

Hollywood is abuzz as Sony's latest horror film, directed by Zach Cregger, has made a significant entrance at the box office. The reboot of the iconic franchise, which opened on September 19, 2026, garnered a staggering $26.3 million domestically on its opening day, emerging as the No. 1 new release according to a report from Variety.
This impressive performance comes at a strategic time as theaters prepare for the fall season when horror films typically attract more attention. The film is showing strong earnings across 3,684 screens, indicating a robust appeal to audiences eager for thrills.
Initial projections suggest that the film could reach approximately $55 million by the end of its opening weekend, potentially marking the largest debut in the history of the "Resident Evil" franchise. Previously, the highest-grossing installment, 2010's Resident Evil: Afterlife, earned $26 million in its opening weekend. This newly established benchmark demonstrates significant growth and interest in this rebooted version of the beloved series.
Directed by Cregger, known for his recent works including Barbarian and Weapons, the film is based on Capcom's popular horror video games. The story features Austin Abrams as a medical courier navigating a zombie outbreak while delivering to Raccoon City General Hospital. While some fans expressed concerns about the absence of established characters from the video game universe, early reviews and audience reactions indicate a positive reception, with Variety's Owen Gleiberman describing it as a “sweetly executed piece of escapist trivia.”
In addition to 'Resident Evil,’ the weekend’s box office contenders include Practical Magic 2, which secured the second spot with a $3.1 million addition to its total, bringing its cumulative earnings to $48.2 million. Other notable films include Spider-Man: Brand New Day, which has amassed a remarkable $944.15 million domestically, and The Odyssey, reaching $609.8 million.
The diversity of genres represented at the box office suggests that audiences are engaging with a range of options, from horror to fantasy and thrillers, making this an interesting time for moviegoing habits.
The strong opening for Zach Cregger's 'Resident Evil' not only highlights the enduring popularity of the franchise but also reflects a successful revival strategy that resonates well with both current fans and newcomers. While it’s too early to predict the long-term success of the reboot, the initial box office figures could indicate a fresh take on the franchise may reinvigorate interest and lead to future projects. As audiences continue to seek thrilling experiences, this film sets the stage for more horror entries in the coming months.
For more details on the film's development, check out our articles on the Resident Evil reboot's anticipations and its initial critical response.
With exciting engagements at the box office, the return of Resident Evil could usher in a new era for horror films in cinemas.
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