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EXCLUSIVE: Jenny Slate (Dying for Sex) has been tapped as the female lead opposite Dylan O’Brien in the Hulu comedy pilot 'Lex'.

Hulu has confirmed that Jenny Slate will star as the female lead opposite Dylan O’Brien in the upcoming comedy pilot titled ‘Lex’. Written by Sean Clements, the comedy centers on Lex (O’Brien), a disgraced former reality star who accidentally films a murder during a $20 Cameo video, leading him into a global conspiracy. The announcement was made by Deadline on September 9, 2026.
Slate, known for her performance in 'Dying for Sex', will portray Holly, a recently fired personal assistant from a tech CEO. She gets entwined in the conspiracy alongside Lex, utilizing her organizational skills and unexpected knowledge of firearms that she has acquired along the way. These character dynamics add depth to the narrative, showcasing their partnership as they aim to clear Lex’s name while simultaneously facing looming dangers from powerful forces chasing them.
‘Lex’ centers around Lex (O’Brien), who unwittingly captures a murder in a Cameo video, thrusting him into immediate peril. This incident escalates into a whirlwind of trouble that forces him into a conspiracy where survival becomes a priority. Holly (Slate) steps in as a reluctant ally, helping Lex leverage her skills to navigate the attempts on their lives.
In addition to Slate and O’Brien, Sean Clements serves as the writer, known for his distinctive sense of humor that intertwines dark comedy with absurd situations. Both Clements and O’Brien are also part of the executive production team alongside Paul Simms, under the banner of 20th Television.
Jenny Slate’s emergence in recent performances has garnered attention, particularly through her role in FX's 'Dying for Sex', streaming on Hulu. Recent projects include her appearance alongside Chris Pine in the indie feature ‘Carousel’, which premiered at the Sundance Film Festival. She's also involved with DreamWorks Animation’s 'Forgotten Island' and is recognized for her standout role in ‘Marcel The Shell With Shoes On’. This diverse repertoire showcases her versatility, making her role in ‘Lex’ all the more significant.
As a comedy pilot, ‘Lex’ aims to capture a wide audience with its unique blend of humor and thrilling plot twists. The chemistry between Slate and O’Brien is anticipated to resonate especially well with fans of character-driven comedies. As viewers increasingly seek out shows that incorporate both comedy and suspense, ‘Lex’ is positioned to carve a niche in Hulu's comedy offerings.
The casting of Jenny Slate alongside Dylan O’Brien marks an exciting development for Hulu’s commitment to producing distinctive content. Both actors have solidified their reputations in the industry, and their collaboration in ‘Lex’ signals Hulu's further investment in original, innovative storytelling that appeals to a modern audience eager for narratives blending laughter with suspense. This pilot could establish a new comedic voice in television that resonates well with viewers who enjoy gripping tales interlaced with humor.
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