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Prime Video has confirmed a live-action adaptation of The Apothecary Diaries, approved by creator Hyūganatsu. Here’s what we know so far.

On September 3, 2026, Prime Video announced that the popular anime adaptation of The Apothecary Diaries is set for a live-action adaptation, titled Intelligence Declassified. This exciting development was confirmed through the platform’s official X handle, marking a significant moment for fans of the franchise.
The announcement comes on the heels of the series’ growing popularity following its successful anime adaptation, which began airing in 2023. The first two seasons of the anime have received acclaim, significantly increasing sales for both the light novel, written by Hyūganatsu, and its manga adaptations.
Hyūganatsu, the creator of The Apothecary Diaries, expressed enthusiasm over the live-action adaptation. She noted that she had reviewed the casting and found it true to her original vision. This approval adds a layer of confidence for fans concerned about the translation of the source material.
In her comments on social media, Hyūganatsu mentioned, "The casting is so spot-on it practically leaps off the page," highlighting her satisfaction with the sets and props used in the production as well. The only cast member revealed so far is Mana Ashida, a well-known Japanese actress and singer, who will portray the central character, Maomao. More casting details are expected to be unveiled later.
While the specifics regarding the number of episodes for Intelligence Declassified have not been revealed, the drama is confirmed to premiere exclusively on Prime Video in 2028. The prospect of a live-action series holds notable significance since the light novel has been a continuous success since its inception in 2014.
As the live-action series is in development, twists in storytelling could arise. Hyūganatsu has described the script as bold and free of awkwardness. While changes might be anticipated, one detail that fans are particularly curious about is Maomao’s hair color, which will reflect the darker shade from the light novel rather than the vibrant green depicted in the anime.
Fans will not have to wait long for more Apothecary Diaries content, as Season 3 of the anime is slated to begin streaming on October 2, 2026. This season will cover key events from Volume 5 of the light novel, where Maomao investigates a series of mysterious occurrences in northern farming villages. The third season will be distinct from its predecessors, as it will only air its first cour this fall, with additional episodes set to release in Spring 2027.
Moreover, the first feature-length movie for the franchise is scheduled to release in Japanese theaters on December 11, 2026, although international fans will have to wait until the following year to view it.
The announcement of the live-action adaptation has already generated significant buzz online, quickly going viral and accumulating millions of impressions. Fans are keen to see how the adaptation will balance staying true to the source material while potentially introducing new story arcs. The approval from Hyūganatsu has been particularly reassuring, leading to heightened anticipation as details continue to emerge.
The live-action adaptation of The Apothecary Diaries signifies a major milestone for the franchise and its dedicated fanbase. With Hyūganatsu’s endorsement, the project promises an engaging portrayal of the beloved series. As interest continues to grow, the upcoming third season and feature film will likely serve to build momentum for the live-action series as its premiere approaches. Fans eagerly await more casting announcements and additional insights into how the adaptation will unfold.
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